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2022 Faculty Research Publications

Basic Science Faculty Research Publications

Faculty are represented in bold.

• Lau KH, Tan AM, Shi Y. New and Emerging Targeted Therapies for Advanced Breast Cancer. Int J Mol Sci. 2022 Feb 18;23(4):2288. doi: 10.3390/ijms23042288. PMID: 35216405; PMCID: PMC8874375.
  
• Tran T, Le U, Shi Y. An effective up-sampling approach for breast cancer prediction with imbalanced data: A machine learning model-based comparative analysis. PLoS One. 2022 May 27;17(5):e0269135. doi: 10.1371/journal.pone.0269135. PMID: 35622821; PMCID: PMC9140301.
  
• Nguyen A, Johanning G, Shi Y. Emerging Novel Combined CAR-T Cell Therapies. Cancers (Basel). 2022 Mar 9;14(6):1403. doi: 10.3390/cancers14061403. PMID: 35326556; PMCID: PMC8945996.
  
  
• Swayzer DV, Gerriets V. Leuprolide. [Updated 2022 Jul 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK551662/.
  
  
• Dinh, S., Pei, X., Shi, Y.; Application of Modeling and Simulation in the Development of Biologics and Biosimilars; pp 467-480; Biologics and Biosimilars Drug Discover and Clinical Applications; Taylor & Francis; Boca Raton, FL; 2022.
  
  
• Taing K, Chen L, Weng HR. Emerging roles of GPR109A in regulation of neuroinflammation in neurological diseases and pain. Neural Regen Res. 2023 Apr;18(4):763-768. doi: 10.4103/1673-5374.354514. PMID: 36204834.
  
  
• Jessica K. Mandula, Shiun Chang, Eslam Mohamed, Rachel Jimenez, Rosa A. Sierra-Mondragon, Darwin C. Chang, Alyssa N. Obermayer, Carlos M. Moran-Segura, Satyajit Das, Julio A. Vazquez-Martinez, Karol Prieto, Ann Chen, Keiran S.M. Smalley, Brian Czerniecki, Peter Forsyth, Richard C. Koya, Brian Ruffell, Juan R. Cubillos-Ruiz, David H. Munn, Timothy I. Shaw, Jose R. Conejo-Garcia, Paulo C. Rodriguez, Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses, Cancer Cell, Volume 40, Issue 10, 2022, Pages 1145-1160.e9, ISSN 1535-6108, https://doi.org/10.1016/j.ccell.2022.08.016. (https://www.sciencedirect.com/science/article/pii/S1535610822003804)
  
• Mandula JK, Chang S, Mohamed E, Jimenez R, Sierra-Mondragon RA, Chang DC, Obermayer AN, Moran-Segura CM, Das S, Vazquez-Martinez JA, Prieto K, Chen A, Smalley KSM, Czerniecki B, Forsyth P, Koya RC, Ruffell B, Cubillos-Ruiz JR, Munn DH, Shaw TI, Conejo-Garcia JR, Rodriguez PC. Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses. Cancer Cell. 2022 Oct 10;40(10):1145-1160.e9. doi: 10.1016/j.ccell.2022.08.016. Epub 2022 Sep 22. PMID: 36150390; PMCID: PMC9561067.
  
  
• Priya K. Manhas, Christiane How-Volkman, Olivia Wu, Satori Iwamoto, Caroline Goswami, Ahmed El-Shamy. (2022). Chapter 4: Vaccines as Biologics in the Era of Pandemic. In Feng, X., Xie, H.-G., Malhotra, A., & Yang, C.F. (Eds.). Biologics and Biosimilars: Drug Discovery and Clinical Applications (1st ed.). CRC Press. https://doi.org/10.1201/9780429485626.
  
  
• Zhou, J and Shi, Y. (2022). Transformative Stem Cell-Based Therapy in Neurological Diseases and Beyond. Feng, X., Xie, H.-G., Malhotra, A., & Yang, C.F. (Eds.), Biologics and Biosimilars: Drug Discovery and Clinical Applications (Chapter 24, Page 385-404). CRC Press. https://doi.org/10.1201/9780429485626.
  
  
• Wang H, Tran TT, Duong KT, Nguyen T, Le UM. Options of Therapeutics and Novel Delivery Systems of Drugs for the Treatment of Melanoma. Mol Pharm. 2022 Dec 5;19(12):4487-4505. doi: 10.1021/acs.molpharmaceut.2c00775. Epub 2022 Oct 28. PMID: 36305753.
  
  
• Begum R, Papia SA, Begum MM, Wang H, Karim R, Sultana R, Das PR, Begum T, Islam MR, Manwar N, Rahman MS. Evaluation of Hepatoprotective Potential of Polyherbal Preparations in CCl4-Induced Hepatotoxicity in Mice. Adv Pharmacol Pharm Sci. 2022 Feb 27;2022:3169500. doi: 10.1155/2022/3169500. PMID: 35265845; PMCID: PMC8898809.
  
• Shaofei Wang, Yubin Li, Mengyao Liu, Hongbin Wang*, Jiajun Fan*. Biologics and Biosimilars: Potential Therapeutics for Autoimmune Renal Diseases. ("Biologics and Biosimilars: Drug Development and Clinical Affairs" (hardback ISBN: 978-1-138-59422-7; T & F cat #: K387158). (CRC Press.) June 2022.
  
• Li Y & Wang H*. Complement: Complement system: past, present, and future. ("Biologics and Biosimilars: Drug Development and Clinical Affairs" (hardback ISBN: 978-1-138-59422-7; T & F cat #: K387158). (CRC Press.) June 2022.
  
• Li Y., Zhang X., Zeng X., Wang S., Wang H*. (2022) Tumor-Associated Macrophages: Therapeutic Targets of Cancer. In: Gupta S., Pathak Y.V. (eds) Macrophage Targeted Delivery Systems. Springer, Cham. https://doi.org/10.1007/978-3-030-84164-5_13.
• Maixner DW, Christy D, Kong L, Viatchenko-Karpinski V, Horner KA, Hooks SB, Weng HR. Phytohormone abscisic acid ameliorates neuropathic pain via regulating LANCL2 protein abundance and glial activation at the spinal cord. Mol Pain. 2022 Apr;18:17448069221107781. doi: 10.1177/17448069221107781. PMID: 35647699; PMCID: PMC9248043.
  
• Mechanisms of Cistromic Repositioning of the Transcription Factor PU. 1. S. Taylor, J. Stauber, O. Bohorquez, B. Bartholdy, E. Schwenger, A. Farahat, et al. Blood 2022 Vol. 140 Issue Supplement 1 Pages 3011-301
  
• Selective Sensing of Darolutamide and Thalidomide in Pharmaceutical Preparations and in Spiked Biofluids. W. Talaat, A. A. Farahat and R. M. Keshk. Biosensors 2022 Vol. 12 Issue 11 Pages 1005.
  
• Thermodynamic Factors That Drive Sequence-Specific DNA Binding of Designed, Synthetic Minor Groove Binding Agents. A. Paul, A. Farahat, D. W. Boykin and W. D. Wilson. Life 2022 Vol. 12 Issue 5 Pages 681.
  
• Synthesis and Structure Determination of 1-(4-Methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1, 2, 3-triazole-4-carbohydrazide. B. M. Kariuki, B. F. Abdel-Wahab, A. Farahat and G. A. El-Hiti. Molbank 2022 Vol. 2022 Issue 2 Pages M1374
  
• Treatment of acanthamoeba or balamuthia trophozoites and/or cysts. D. W. Boykin, D. E. Kyle, C. A. Rice and A. Farahat. US Patent App. 17/286,058 2022.
• Reactivity of 4-Bromoacetyl-1,2,3-triazoles towards Amines and Phenols: Synthesis and Antimicrobial Activity of Novel Heterocycles. H. A. M. Bakr F. Abdel-Wahab, Abdelbasset A. Farahat, Benson M. Kariuki, Gamal A. El-Hiti. Heterocycles 2022 Vol. 104 Issue 9 Pages 1601-1613.
  
• John K Cusick, Pranshul Goel, Justin Shiann Tang, Alyssa Abram, Yennie Shyu, Valerie Gerriets; Improving the Effectiveness of Combining Voice-Over PowerPoint Presentations and Review Games for Delivering Immunology Content.. J Immunol 1 May 2022; 208 (1_Supplement): 106.01. https://doi.org/10.4049/jimmunol.208.Supp.106.01

Clinical Science Faculty Research Publications

Faculty are represented in bold.

• Ghnenis A, Padmanabhan V, Vyas A. Sexual dimorphism in testosterone programming of cardiomyocyte development in sheep. Am J Physiol Heart Circ Physiol. 2022 Apr 1;322(4):H607-H621. doi: 10.1152/ajpheart.00691.2021. Epub 2022 Feb 4. PMID: 35119334; PMCID: PMC8957338
• Vinall R, Chen Q, Talbott G, Ramsamooj R, Dang A, Tepper CG, Borowsky A. Use of RNA-Seq and a Transgenic Mouse Model to Identify Genes Which May Contribute to Mutant p53-Driven Prostate Cancer Initiation. Biology (Basel). 2022 Jan 29;11(2):218. doi: 10.3390/biology11020218. PMID: 35205085; PMCID: PMC8869245.
  
• Sathe A., Lindars D., Sathe P., Nallapareddy R., Grennan T., Bilateral Renal Oncocytoma: Active Surveillance vs. Partial Nephrectomy. Cureus. 2022 Feb 16. (PMID: 35350482).
  
• Janardhan N, Roy PG, Vyas AK. Impact of maternal substance use on offspring's cardiovascular health. Toxicol Appl Pharmacol. 2022 Sep 1;450:116164. doi: 10.1016/j.taap.2022.116164. Epub 2022 Jul 14. PMID: 35842136.
  
• Vyas D, Umemoto KK, Vyas A, Bhatt DL. Procedure room innovation during the COVID-19 crisis: Protecting healthcare workers while learning from history. iScience. 2022 Jul 16;25(8):104704. doi: 10.1016/j.isci.2022.104704. PMID: 35854813; PMCID: PMC9287126.
  
• Jundi L, Sathe A, Lai N, Lui F. My Head is Getting Bigger: Macrocephaly with Cause Shown on CT Head – Clinical Image. Asp Biomed Clin Case Rep. 2022 Aug 03;5(2):89-90.
  
• Lui, F., Geraghty,J.J., Nagourney, A.J., Khatchadourian, P., Katiby, Y.N., Thiemann, A. M.. Case Report – An Unusual Case of Vanishing White Matter Disease with Cataract and Exaggerated Stress Response. Acta Scientific Neurology 2022;5(3):11-15. DOI: 10.31080/ASNE.2022.05.0484.
  
• Aleeha Noon, Lillian Jundi, John Geraghty, Forshing Lui. Adult-Onset MELAS in a 28-year-old Female Presenting with Visual Loss and Type 1 Diabetes Mellitus: A Case Report. Adv Case Stud. 3(2). AICS.000562. 2022. DOI: 31031/AICS.2022.03.000562.
  
• Stephen Howell, Steven Wright, Jason Chang, Forshing Lui. Toxic Encephalopathy following Methamphetamine, MDMA, and Marijuana Intoxication: A Case Report. Adv Case Stud. 3(2). AICS.000564. 2022. DOI: 10.31031/AICS.2022.03.000564.

• Ananth S, Umemoto KK, Vyas D. Hydrodissection in Laparoscopic Cholecystectomies for Gangrenous Gallbladders. Int J Gen Med. 2022 Oct 10;15:7735-7738. doi: 10.2147/IJGM.S364289. PMID: 36249897; PMCID: PMC9563322.
  
• Malhotra A, Yang C, Feng X. Application of constructivism and cognitive flexibility theory to build a Comprehensive, Integrated, Multimodal Interprofessional Education and Practice (CIM-IPEP) program. J Interprof Care. 2021 May 18:1-6. doi: 10.1080/13561820.2021.1900802. Epub ahead of print. PMID: 34003047.

• Kotsopoulou I, Vyas AK, Cory MJ, et al. Developmental changes of the fetal and neonatal thyroid gland and functional consequences on the cardiovascular system. Journal of Perinatology : Official Journal of the California Perinatal Association. 2022 Dec;42(12):1576-1586. DOI: 10.1038/s41372-022-01559-3. PMID: 36376450.
  
• Muhar B K, Cho S, Sidhu A S, Chang J, Lui F. (January 04, 2023) Isolated Hypoglossal Nerve Palsy Secondary to Oligosecretory Multiple Myeloma. Cureus 15(1): e33361. doi:10.7759/cureus.33361.
  
• Pia, S., Looi D, Stone R, Zhong N, Lui F. (December 28, 2022) An Unusual Case of Two Paraneoplastic Neurological Syndromes in a Patient With Lung Cancer. Cureus 14(12): e33047. doi:10.7759/cureus.33047.
  
• Seo Y, Reed M, Chang J S, Lui F. (December 08, 2022) Wernicke’s Encephalopathy Presenting With Confusion in a Patient With Schizophrenia. Cureus 14(12): e32320. DOI 10.7759/cureus.32320.
  
• Krista Tenerelli, Alexander Nagourney, Jason Chang and Forshing Lui. Case Report - Early Recognition of Methanol Poisoning. Acta Scientific Neurology 5(9), 2022.
  
• Forshing Lui, Ning Zhong, Kaho Wong, Stella Knowlton, Jessa Alcaide, Michael Ysit. Dysfunction of the Glymphatic System is the Cause of Amyloid Angiopathy-Strong Evidence from a Case and Review of the Literature. Nov Res Sci. 11(5). NRS. 000773. 2022. DOI: 10.31031/NRS.2022.11.000773.
  
• Meghana Pisupati, Emily L Siegler, Ning Zhong, Forshing Lui. Case Report-Subdural Empyema as a Life-threatening Complication of Acute Sinusitis. Adv Case Stud. 3(4). AICS.000567. 2022. DOI: 10.31031/AICS.2022.03.000567.
  
• Gavin Zanella, Nicholas Baltar, Forshing Lui, Ning Zhong, Kaho Wong. Heidenhain Variant Creutzfeldt-Jakob Disease Identified with RT-QuIC Assay: A Case Report. Adv Case Stud. 3(2). AICS.000561. 2022. DOI: 10.31031/AICS.2022.03.000561.
  
• Coifman, R.E. and Yang, C.F., “Vaccine Delivery by Precipitation (VDBP) Lessons from Poison Ivy for Protein Antigens in General and Specifically for SARS Co-V2”, Eur J Respir Med, 2022, 4:2.
  
• Young, E. H. Gulia, K and Yang, C. Chapter “Regulatory Aspects of Biologics and Biosimilars”, Book, “Biologics and Biosimilars: Drug Development and Clinical Affairs”, ISBN: 978-1-138-59422-7; T & F cat #: K387158, 2022, CRC Press in production.
  
• Wong, T. and Yang, C. Chapter “Delivery of Biologics, Biosimilars and Vaccines”, Book, “Biologics and Biosimilars: Drug Development and Clinical Affairs”, ISBN: 978-1-138-59422-7; T & F cat #: K387158, 2022, CRC Press in production.
  
• Herr, D. Y., Young, E. H. and Yang, C. Chapter “Machine Learning Applications in Biologics and Biosimilars”, Book, “Biologics and Biosimilars: Drug Development and Clinical Affairs”, ISBN: 978-1-138-59422-7; T & F cat #: K387158, 2022, CRC Press in production.
  
• Muhar BK, Penney A. Kotchoni S. 2022. "Biologics and Biosimilars." Biologics and Biosimilars: Drug Discovery and Clinical Application, edited by Xiadong Feng, Hong-Guang Xie, Ashim Malhotra, Catherine Yang. 33-48. Boca Raton. CRC Press. 9780429485626.
  
• Munakomi S, Lui F. Caloric Reflex Test. In StatPearls [Internet] 2022 Feb 17. StatPearls Publishing.
  
• Rupareliya C, Lui F. Moyamoya Disease. In StatPearls [Internet] 2022 Apr 9. StatPearls Publishing.

Clinical Medicine Faculty Research Publications

Faculty are represented in bold.

• Ma, V.X.T, Sauer, A.J., and Ranasinghe, L. (2022) Amiodarone versus Lidocaine Therapy in the Adult Cardiac Arrest Algorithm for VF/pVT/PEA/Asystole. International J. of Biomed Research. 2(3): DOI: 10.31579/IJBR-2021/058. 
• Khanna, Niloufar, Peralta Samantha, Zhang, Rayven, Thiesen, Jordan DO, Ranasinghe, Leonard (2022). Thyroid Storm: An Elusive but Deadly Diagnosis -- A Case Report. International J. of Biomed Research. 2(3): DOI: 10.31579/IJBR-2021/057.
  
• Combs J, Narra T, Ou C, Velaz DM, Chatten-Brown J, Ranasinghe L. Post-partum Eclampsia Complicated by Cerebral Venous Thrombosis: Case Report. Asp Biomed Clin Case Rep. 2022 Jan 22;5(1):18-24. DOI: 10.36502/2022/ASJBCCR.6257.
  
• Shi VY, Burney W, Shakhbazova A, Pan A, Hassoun LA, Sharma S, Sivamani RK. The Effect of Synthetic Acetylhexapeptide-8 (AH8) on Sebaceous Function. Int J Cosmet Sci. 2022 Jun 12. doi: 10.1111/ics.12795. Epub ahead of print. PMID: 35690997.
  
• Maheta, B., Quach, D., Goswami, K., Ranasinghe, N., Ranasinghe, L. “MRSA Induced Septic Embolism in an Intravenous Drug User: How to Diagnose and Manage Septic Embolism.” American Journal of Biomedical Science & Research. June 28, 2022. 16(4). AJBSR.MS.ID.002260. ISSN: 2642-1747 DOI: 10.34297/AJBSR.2022.16.002260; https://biomedgrid.com/volume16-issue4.php.
  
• Narwan A, Sauer A, Talwar T, Willes O, Ranasinghe N, Ranasinghe L. A Rare Presentation of SMA Vasculitis with Chest and Upper Back Pain: Case Report. Asp Biomed Clin Case Rep. 2022 Jul 25;5(2):79-83.
  
• Dang R, Eggleton J , Habibe M, Alhadi S, Kessler M. et all (2022) A Rare Case of Mastoiditis in an Adult Patient. J. Archives of Medical Case Reports and Case Study, 5(5); DOI:10.31579/2692-9392/119 (Leonard Ranasinghe).
  
• Shi VY, Burney W, Shakhbazova A, Pan A, Hassoun LA, Sharma S, Sivamani RK. The effect of synthetic acetylhexapeptide-8 (AH8) on sebaceous function. Int J Cosmet Sci. 2022 Jun 12. doi: 10.1111/ics.12795. Epub ahead of print. PMID: 35690997.
  
• Wu H, Gabriel TA, Burney WA, Chambers CJ, Pan A, Sivamani RK. Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance. Arch Dermatol Res. 2022 Dec 11. doi: 10.1007/s00403-022-02514-0. Epub ahead of print. PMID: 36502500.
  
• Eggleton J, Yu K, Dhaliwal A, Clarke C, Afzali A, Hutchison J, Ranasinghe L., SARS-COV-2 Positive Patient with Fournier's Gangrene and Multiorgan Compications. Curr Tr Clin & Med Sci. 2(5): 2021. CTCMS.MS.ID.000548. DOI: 10.33552/CTCMS.2021.02.000548.
  
• Patel Amy, Hyer Matthew, Heydarlou Dorsa, Thiemann, Anna, Kayali Mohammad. et all (2022) An Unusual Case of Osteomyelitis in a Pediatric Patient. J. Biomedical Research and Clinical Reviews. 7(2); DOI:10.31579/2692-9406/131 (Leonard Ranasinghe).